ZINC4658552 (Padil)
| Added | Available | Since | Mwt | logP | Heavy Atoms | Tranche | Download |
|---|---|---|---|---|---|---|---|
| 2005-12-22 | In-Stock | 2015-08-07 | 75.067 | -0.97 | 5 | ABAA |
|
Find Decoys
Available 3D Representations
| pH range | Net charge |
H-bond donors |
H-bond acceptors |
tPSA Ų | Rotatable bonds |
Apolar desolvationkcal/mol |
Polar desolvationkcal/mol |
Download |
|---|---|---|---|---|---|---|---|---|
| Reference | 0 | 1 | 2 | 67 | 1 | -0.44 | -40.35 |
|
391 Items Total
Vendors (68 Total)
-
- 12-1210|SAJ
- 1295800|USP
- 15527|SIAL
- 219517|ALDRICH
- 241261|ALDRICH
- 33226|SIAL
- 410225|SIAL
- 50046|SIGMA
- 50049|SIAL
- 50050|SIAL
- 50052|SIAL
- 50058|SIAL
- 55097|SIAL
- 67419|SIGMA
- 76524|SIAL
- 94119|SIAL
- G0450000|SIAL
- G2879|SIGMA
- G5417|SIGMA
- G6761|SIGMA
- G7126|SIGMA
- G7403|SIGMA
- G8790|SIGMA
- G8898|SIGMA
- PHG0016|SIGMA
- PHR1111|SIAL
- V900144|VETEC
- W328707|ALDRICH
-
- A6808
- A7190
-
- 163
- 164
- 21750
-
- CP27217
- CP27404
-
- JZ0518
-
- CUR-0014574
- CUR-0101231
-
- DB-029870
-
- BB0265974
-
- SCF13803
-
- BBS-00003777
-
- SC-26815
- SC-26884
-
- SC-26815
- SC-26884
-
- 50A149332
- 50A260984
- 50C363177
-
- AM001784
- AM003800
- AM003801
- AM004148
- AM004337
- AM004509
- AM005552
- AM005689
- AM014549
- AM016013
- AM018082
- AM019951
- AM020481
- AM021948
- AM022357
- AM022913
- AM022995
- AM023729
- AM024602
- AM025322
- AM026633
- AM027842
- AM029337
- AM030121
- AM031421
- AM032112
- AM035685
- AM036492
- BT000103
- DR000119
- DR002634
- IN012983
- OR025827
- OR034930
- OR035370
- OR035516
- OR036314
- OR038657
- OR050438
- OR053885
- OR055356
- OR059245
- OR061315
- OR068368
- OR191975
- OR214936
- OR214937
- OR215916
- OR220029
- OR220030
- OR222708
- OR222911
- OR226105
- OR226291
- OR231801
- OR231802
- OR232535
- OR239500
- OR247374
- OR249226
- OR254541
- OR255195
- OR262573
- OR276962
- OR292450
- OR328514
- OR333179
- OR333740
- OR342336
- OR375161
-
- LN00195395
- LN00196505
- LN00196869
- LN00198419
- LN00200478
- LN00200572
- LN00244389
- LN00338421
- LN01270492
- LN01270493
- LN01294939
- LN01308181
- LN01742431
- LN01742466
- LN02138645
-
- SC-26815
69 Items Total
Annotated Catalogs (40 Total)
-
- BIE005477
- BIE020716
- BIE123371
-
- 55751-56-9
-
- C00037_1
- C00037_2
-
- CPD-8569
- GLY
-
- Fabaceae-(3803)
- Fabales-(72025)
- Glycine-(3846)
- Poaceae-(4479)
-
- GLY
- GLY_LEO2
- GLY_LEO2H
- GLY_LFOH
- GLY_LFZW
-
- SW00027
-
- tcm03_003486
-
- UNPD100602
2 Total Observations
Activities based on ChEMBL 20
| Gene Name | Class / Organism | pKi (L.E.) | Observations |
|---|---|---|---|
| GRIN1: Glutamate receptor ionotropic, NMDA 1 | ion channel / LGIC (E) | 6.60 (1.85) | 2 |
Run SEA
SEA Predictions based on ChEMBL 20
| Gene | Description | Target Class | P-Value | Max Tc |
|---|---|---|---|---|
| GABRG1 | Gamma-aminobutyric acid receptor subunit gamma-1 | ion channel / LGIC | 0 | 47 |
| GABRR1 | Gamma-aminobutyric acid receptor subunit rho-1 | ion channel / LGIC | 28 | 47 |
Find All
Interesting Analogs
Scaffold of this compound
ZINC4658552
Nothing else with this scaffold
Substance Rings
This compound has no patterns of concern (or they have not yet been computed).
Molecular Patterns (Warnings, etc.)
References
| Doc | Year | Journal | Volume | Issue | Pages | Link |
|---|---|---|---|---|---|---|
| 3119 | 1999 | Bioorg. Med. Chem. Lett. | 9 | 10 | 1409–1414 | 10360746 |
| 11444 | 1992 | J. Med. Chem. | 35 | 2 | 233–241 | 1310117 |
View All 27 Clinical Trials
| Trial ID | Title | Status | Phase | Start Date | Condition(s) | Drug(s) |
|---|---|---|---|---|---|---|
| NCT02348762 | Energetics and Function in Older Humans | Recruiting | Phase 1 | Nov 2014 |
Muscle Weakness
Erythrocyte Glutathione Deficiency
Aging
|
Cysteine (as n-acetylcysteine) and Glycine
|
| NCT02348775 | Glutathione and Function in HIV Patients | Recruiting | Phase 1 | Nov 2014 |
Erythrocyte Glutathione Deficiency
HIV Infection
|
Cysteine (as n-acetylcysteine) and glycine
|
| NCT02064881 | Efficacy Study of Metformin Glycinate on Postprandial Lipemia | Not yet recruiting | Phase 2/Phase 3 | Jun 2014 |
Type 2 Diabetes
|
Metformin glycinate
Metformin Hydrochloride
|
| NCT02108691 | Effect of Intake of Glycin Max (L.) Merr. Peel Extract on Body Fat and Body Weight | Not yet recruiting | Phase 2/Phase 3 | May 2014 |
Obesity
|
Glycin max(L.) Merr. peel extract
Placebo
|
| NCT02128971 | A Study to Compare the Gastrointestinal Tolerability of Ferrochel®, Sumalate®,Ferrous Fumarate, Ferrous Sulfate, Ferric Glycinate, and Placebo | Recruiting | Phase 2 | Apr 2014 |
Anemia
|
Ferrochel® 90 mg
Sumalate® 90 mg
Ferrous fumarate 90 mg
Ferrous Sulfate 90 mg
Ferric Glycinate 90 mg
Placebo
|
Additional Identifiers (Synonyms/CAS Numbers/etc.)
- CAS Numbers
- ATC Code(s)
- WHO Name(s)
- Molecule Names
-
- GLYCINE
- Synonyms