ZINC6661227 (Histidine)

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Added Available Since Mwt logP Heavy Atoms Tranche Download
2006-04-12 In-Stock 2015-08-07 155.157 -0.636 11 ABAA
ZINC6661227
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pH range Net
charge		 H-bond
donors		 H-bond
acceptors		 tPSA Ų Rotatable
bonds		 Apolar
desolvationkcal/mol		 Polar
desolvationkcal/mol		 Download
Reference 0 2 3 96 3 1.5 -37.73
Mid pH (7.4) 0 2 3 96 3 1.54 -38.68
Low pH (6.4) 1 2 2 97 3 2.06 -79.31
328 Items Total

Vendors (74 Total)

Aldrich CPR
Bachem
Molport
Specs
Bioactive Toronto Research Chemicals
Building Blocks Alfa-Aesar
Building Blocks Combi-Blocks
Building Blocks Enamine Building Blocks
Building Blocks Frontier Scientific Services BB
Building Blocks Matrix Scientific
Building Blocks Molport BB
Building Blocks Sigma Aldrich (Building Blocks)
Alinda
  • IBS-L0126212
APExBIO
  • A7199
Bioactive Apollo Scientific Bioactives
Aronis
Bosche Scientific
  • H6280
  • H6336
Capot Chemical
Chem-Impex International
  • 179
  • 181
  • 1951
Creative Peptides
  • CP01001
  • CP01002
  • CP01003
Fluorochem
IBScreen NP
Indofine
Innovapharm
  • STT-00378018
NCI Plated 2007
Oakwood Chemical
Pharmeks
Pi Chemicals
  • PI-14273
TimTec
UORSY
Vesino Industrial Co Ltd
Building Blocks Acros Organics
Building Blocks AK Scientific
Building Blocks Ark Pharm Building Blocks
Building Blocks AstaTech
Building Blocks BePharm Building Blocks
Building Blocks Bide Pharmatech BB
Building Blocks BioSynth
Building Blocks BOC Sciences BB
Building Blocks Curpys Building Blocks
  • CUR-0010761
  • CUR-0016710
  • CUR-0025929
Building Blocks Debye Scientific Building Blocks
  • DB-029959
Building Blocks FineTech
Building Blocks Hong Kong Chem Here
  • 7048-02-4
  • SCA45572
Building Blocks IBScreen BuildingBlocks
Building Blocks Innovapharm Building Blocks
  • BBS-00004484
  • BBS-00027541
  • BBS-00028831
  • BBS-00028940
Building Blocks Lab Seeker Building Blocks
  • SC-09574
  • SC-09575
  • SC-15765
  • SC-48559
  • SC-48587
Building Blocks Life Chemicals Building Blocks
Building Blocks Molepedia
Building Blocks Nanjing Kaimubo Pharmatech
Building Blocks Oxchem Corp.
Building Blocks Pharmeks BB
Building Blocks StruChem BB
  • SC-09574
  • SC-09575
  • SC-15765
  • SC-48559
  • SC-48587
Building Blocks Tetrahedron Building Blocks
Building Blocks TimTec Building Blocks
Building Blocks W&J PharmaChem
  • 50A179087
  • 50A199604
  • 50A245730
  • 50C254880
1717 CheMall Corporation
  • AM004319
  • AM004338
  • AM004834
  • AM004835
  • AM004911
  • AM005472
  • AM005496
  • AM008372
  • AM013168
  • AM020708
  • AM020734
  • AM021264
  • AM024411
  • AM024815
  • AM025734
  • AM026484
  • AM030396
  • AM031185
  • AM031394
  • AM032808
  • AM032809
  • AM038596
  • BT000184
  • HE009272
  • HE010243
  • HE020680
  • HE020806
  • HE033453
  • HE046518
  • HE056326
  • HE058049
  • HE065194
  • HE303855
  • HE309098
  • HE311535
  • HE312961
  • HE313604
  • HE334620
  • HE346583
  • HE384391
  • HE388205
  • HE412748
Alfa Chemistry Make-on-demand
Ambinter
eMolecules
Molport Make-on-demand
Otava (Virtual)
Tractus
Wonderchem
Building Blocks Angene BB Make-on-demand
Building Blocks Angene Building Blocks
Building Blocks Ark Pharm BB Make-on-demand
Building Blocks eMolecules Building Blocks
Building Blocks FCH Group Building Blocks
Building Blocks Lab Network Building Blocks
  • LN00188368
  • LN00193432
  • LN00195681
  • LN00202149
  • LN00223776
  • LN01344747
  • LN02020015
Building Blocks Molcore
Building Blocks Nanjing Raymon Biotech Co Ltd
  • R000ZQ
Building Blocks PBMR Labs Building Blocks
  • RBK_094290
Building Blocks StruChem BB make-on-demand
  • SC-09575
  • SC-15765
  • SC-48559
  • SC-48587
Building Blocks SynQuest Building Blocks
85 Items Total

Annotated Catalogs (39 Total)

Biocore Pharmatech
  • BIE031331
  • BIE055545
  • BIE138478
Santiago.cz
  • 1007-42-7
  • 645-35-2
Building Blocks Element Store BB
Aggregators
  • NCGC00093950-01
Endogenous Human Metabolites Metabolites Bioactive Amino acids and their derivatives (EFI)
  • C00135_2
  • C00135_4
  • C00135_6
  • C00135_8
BindingDB.org
Bioactive Biocyc via PubChem
  • HIS
Bioactive Bitter DB
Bioactive Bovine Metabolome
Bioactive ChEBI
ChEMBL20
ChEMBL 21
ChEMBL23
In Man ChEMBL DrugStore
In Man CSF Metabolome SMPDB
Bioactive DrugBank All
World Drugs DrugBank-approved
FDA Approved Drugs DrugBank FDA only
World Drugs DrugBank-nutriceuticals
Bioactive E. coli Metabolome Database
FDA-approved drugs (via DSSTOX)
In Man Food Database
In Man HMDB Drug
In Man HMDB Food
In Man Human Metabolome Database
Bioactive IUPHAR Database
Bioactive KEGG-C via PubChem
In Man KEGG-D via PubChem
Bioactive KEGG via PubChem
Bioactive PDSP KiDB
Bioactive Protein Databank
  • HIS
  • HIS_LEO2
  • HIS_LEO2_DHD1
  • HIS_LEO2_DHE2
  • HIS_LEO2H
  • HIS_LEO2H_DHD1
  • HIS_LEO2H_DHE2
  • HIS_LFOH
  • HIS_LFOH_DHD1
  • HIS_LFOH_DHE2
  • HIS_LFZW
  • HIS_LFZW_DHD1
  • HIS_LFZW_DHE2
In Man Serum Metabolome
SMDC Public
In Man SMPDB Small Molecule Pathway Database
Bioactive StreptomeDB
Sweetlead
  • SW00362
UNPD
  • UNPD182729
In Man Urine Metabolome
Bioactive Yeast Metabolome

Activities based on ChEMBL 20

Run SEA View All 16

SEA Predictions based on ChEMBL 20

Gene Description Target Class P-Value Max Tc
HDH Histidinol dehydrogenase, chloroplastic enzyme / enzyme-other 0 64
HISD Histidinol dehydrogenase enzyme / enzyme-other 0 78
IDE Insulin-degrading enzyme enzyme / enzyme-other 0 40
HRH4 Histamine H4 receptor membrane receptor / GPCR-A 27 41
CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 auxiliary transport protein / atp-ca-a2d 27 43
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Interesting Analogs

Scaffold of this compound

ZINC6661227

ZINC6661227

6661404 ZINC6661404

Sources of Ambiguity Find More

Substance Rings

imidazole

Molecular Patterns (Warnings, etc.)

carboxylate-sp3
Weak electrophile
amine-sp3-1
reagent
enolizable ketone
reagent

References

This substance is not reported in any publications per ChEMBL.

Clinical Trials

Trial ID Title Status Phase Start Date Condition(s) Drug(s)
NCT00811785 Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency Recruiting Phase 3 Dec 2008
Unexplained Copper Deficiency
Menkes Disease
Occipital Horn Syndrome
Copper Histidine
NCT00001262 Copper Histidine Therapy for Menkes Diseases Completed Phase 2 Jun 1990
Kinky Hair Syndrome
Copper Histidine

Additional Identifiers (Synonyms/CAS Numbers/etc.)

CAS Numbers
Molecule Names
  • HISTIDINE
  • HISTIDINE MONOHYDROCHLORIDE
Synonyms

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