Welcome to ZINC, a free database of commercially-available compounds for virtual screening. ZINC contains over 230 million purchasable compounds in ready-to-dock, 3D formats. ZINC also contains over 750 million purchasable compounds you can search for analogs in under a minute.

ZINC is provided by the Irwin and Shoichet Laboratories in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF). We thank NIGMS for financial support (GM71896).

To cite ZINC, please reference: Sterling and Irwin, J. Chem. Inf. Model, 2015 http://pubs.acs.org/doi/abs/10.1021/acs.jcim.5b00559. You may also wish to cite our previous papers: Irwin, Sterling, Mysinger, Bolstad and Coleman, J. Chem. Inf. Model, 2012 DOI: 10.1021/ci3001277 or Irwin and Shoichet, J. Chem. Inf. Model. 2005;45(1):177-82 PDF, DOI.

ZINC15 News

  • 2018-02-14 - ZINC reaches 213,235,528 purchasable leadlike 3D!
  • 2018-02-13 - ZINC reaches 736,001,654 purchasable molecules 2D!
  • 2018-01-14 - Klara Anu is born! Welcome Klara Anu, sister to Lisa!
  • 2018-01-01 - Chinzo Dandar joins our team. Welcome Chinzo! Follow us on twitter @chem4biology Known limitations What's new
Caveat Emptor: We do not guarantee the quality of any molecule for any purpose and take no responsibility for errors arising from the use of this database. ZINC is provided in the hope that it will be useful, but you must use it at your own risk.